Description
What Is TB-500?
TB-500 is the lab-made counterpart of Thymosin Beta-4, a peptide found in nearly all human and animal cells. Research suggests it may support wound healing, stimulate blood vessel formation, regulate inflammation, and aid tissue repair. Much of its activity relates to its interaction with actin—a protein essential for cell structure and movement.
Due to these regenerative properties, TB-500 has become a focus in research on injury recovery, cardiovascular health, neurodegenerative conditions, and anti-aging strategies.
How TB-500 Works
The primary mechanism of TB-500 centers on actin binding. Actin plays a critical role in maintaining cell shape, movement, and muscle fiber formation. By supporting actin function, TB-500 helps enable tissue regeneration, structural cell integrity, and repair processes throughout the body.
Peptide Details
- Sequence: Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser
- Molecular Formula: C212H350N56O78S
- Molar Mass: 4963.44 g/mol
- CAS Number: 77581-33-4
- PubChem ID: 16132341
Areas of Scientific Research
1. Nervous System Repair
Studies in animal models suggest that TB-500 promotes healing in the brain and spinal cord by supporting cells that nourish and protect neurons.
2. Blood Vessel Formation
TB-500 stimulates VEGF (vascular endothelial growth factor), essential for capillary growth, wound healing, tissue oxygenation, and even hair growth.
3. Hair Growth
Research on mice indicates that elevated Thymosin Beta-4 levels promote faster regrowth and healthier follicles.
4. Antibiotic Support
In studies, TB-500 enhanced the effectiveness of antibiotics like ciprofloxacin, reducing infection severity and improving healing outcomes.
5. Cardiovascular Benefits
May aid the heart by encouraging new blood vessel growth, improving cell survival after a heart attack, and reducing fibrosis.
6. Neurodegenerative Disease Potential
Early research suggests TB-500 supports autophagy (the brain’s cleaning process), which may help conditions like Alzheimer’s or prion diseases.
7. Wide Range of Applications
Ongoing studies explore its role in immune modulation, trauma recovery, chronic conditions, and tissue regeneration.
Research Use Only
TB-500 is intended for scientific and laboratory research only. It is not approved for human or veterinary use. Any references to potential applications are based solely on preclinical findings.