Description
PT-141 Peptide — Research Use Only
PT-141, also known in published literature as bremelanotide, is a synthetic melanocortin receptor agonist studied for its interaction with melanocortin signaling pathways. It is a cyclic peptide analog derived from melanotan II, which itself is related to alpha-melanocyte-stimulating hormone, or α-MSH.
PT-141 has been investigated in preclinical and clinical research settings for its activity at melanocortin receptors, particularly MC4R and MC1R. These receptor systems are involved in a range of biological processes, including neuroendocrine signaling, inflammatory response pathways, vascular biology, and pigment-related mechanisms.
AminoVault offers PT-141 strictly as a laboratory research compound. This material is intended for qualified research professionals and institutions only.
Product Overview
PT-141 is commonly referenced in scientific literature for its role as a melanocortin receptor agonist. Unlike compounds that act directly on peripheral vascular pathways, PT-141 has been studied for central nervous system–mediated melanocortin activity.
Research interest in PT-141 has included melanocortin receptor signaling, receptor selectivity, neurobiological pathways, inflammatory response models, vascular response models, and related peptide structure-activity relationships.
Chemical Profile
Compound Name: PT-141
Also Known As: Bremelanotide
Peptide Sequence: Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys
Molecular Formula: C50H68N14O10
Molecular Weight: 1025.18 g/mol
CAS Number: 189691-06-3
PubChem CID: 9941379
Areas of Scientific Research
Melanocortin Receptor Signaling
PT-141 has been studied for its activity at melanocortin receptors, especially MC4R and MC1R. These receptors are part of a broader signaling network involved in neuroendocrine regulation, immune response, pigmentation biology, and vascular function.
Neurobiological Research
Because PT-141 is associated with central melanocortin signaling, it has been used in research exploring neurological and behavioral pathways connected to receptor activation. Studies have examined how melanocortin receptor modulation may influence signaling systems distinct from direct peripheral vascular mechanisms.
Vascular and Hemodynamic Models
Published research has examined melanocortin receptor agonists, including PT-141-related compounds, in experimental models involving vascular response and acute circulatory stress. These studies are intended to better understand receptor-mediated biological pathways and are not indicative of approved use for any condition.
Inflammation and Immune Pathway Research
Melanocortin receptors have been investigated for their role in inflammatory and immune response signaling. PT-141 has appeared in research related to these pathways, including exploratory studies in preclinical models.
MC1R and Cellular Response Research
MC1R is involved in pigmentation biology and cellular response mechanisms. PT-141’s receptor activity has contributed to scientific interest in melanocortin signaling and related cellular pathways, including research connected to oxidative stress response and DNA repair mechanisms.
Research Applications
PT-141 continues to be studied as part of broader research into melanocortin receptor biology, peptide-receptor interactions, neuroendocrine signaling, vascular response, inflammation, and structure-activity relationships among synthetic peptide analogs.
Research Use Disclaimer
PT-141 offered by AminoVault is intended strictly for laboratory research use only. It is not a drug, food, cosmetic, dietary supplement, or consumer product. It is not intended for human or veterinary use, diagnosis, treatment, cure, mitigation, or prevention of any disease or medical condition.
This product should be handled only by qualified professionals in properly equipped research settings.
